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Illustration by Roxanna Bikadoroff. This book was featured on the season finale of Lost (spoiler alert if you haven't seen it.) Jacob reads from it as John Locke falls from a high window behind him and hits the ground. Amazon says it's a "...collection of nine short stories by Flannery O'connor, published posthumously in 1965. The flawed characters of each story are fully revealed in apocalyptic moments of conflict and violence that are presented with comic detachment." Thanks for the info, Cat. You can read more about the possible connection of this book to the series here:
http://thelaverytory.blogspot.com/2009/05/lost-and-everything-that-rises-must.html